Mounjaro (Tirzepatide) Singapore: Complete Guide
Last Updated: October 2026
Mounjaro contains tirzepatide, a prescription medicine that acts on the GIP and GLP-1 receptors. It is used for appropriate adults with type 2 diabetes and, where indicated, for weight management alongside a reduced-calorie diet and increased physical activity.
This guide explains Mounjaro and tirzepatide in Singapore, including how it works, who may be suitable, clinical evidence, pricing, dosing, side effects, and the difference between Mounjaro and Zepbound.
Treatment suitability requires an individual medical assessment. Information on this page does not guarantee a prescription or predict an individual’s results.
What is Mounjaro (Tirzepatide)?
Mounjaro is a brand of prescription medicine containing tirzepatide as its active ingredient.
Tirzepatide acts on two hormone pathways involved in glucose regulation and appetite: glucose-dependent insulinotropic polypeptide, or GIP, and glucagon-like peptide-1, or GLP-1.
The names describe different things:
- Mounjaro identifies a branded medicine.
- Tirzepatide identifies its active ingredient.
When reading about treatment, it is important to check the specific product, formulation and local instructions rather than relying on the active ingredient’s name alone.
Is Tirzepatide Available in Singapore?
Yes. Tirzepatide products are registered in Singapore as prescription medicines. Actual supply depends on the formulation, healthcare provider and current availability.
The HSA registration record for Mounjaro KwikPen lists approval of the 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg and 15 mg formulations on 18 June 2025.
The listed indications include treatment of adults with insufficiently controlled type 2 diabetes and weight management in eligible adults.
For weight management, the published indication includes:
- BMI of 30 kg/m² or above, or
- BMI of 27 kg/m² to below 30 kg/m² with at least one weight-related condition.
Registration does not guarantee that every strength is currently supplied. Our article on Mounjaro 12.5 mg registration and availability explores this distinction.
How Does Mounjaro Work?
Tirzepatide activates GIP and GLP-1 receptors involved in appetite and blood glucose regulation. Its effects include reducing food intake and supporting glucose-dependent insulin secretion.
GLP-1
GLP-1 receptor activation affects appetite, glucose regulation and stomach emptying.
GIP
GIP is involved in glucose-dependent insulin secretion. Tirzepatide activates this pathway alongside GLP-1.
The dual mechanism describes how the medicine works; it does not establish that it is the appropriate treatment for every patient. Individual response and tolerability vary.
Who May Be Suitable for Mounjaro?
For weight management, the published Singapore indication includes adults with:
- BMI ≥30 kg/m², or
- BMI ≥27 kg/m² to <30 kg/m² with at least one weight-related condition.
Examples of weight-related health conditions include hypertension, abnormal blood lipids, obstructive sleep apnoea, cardiovascular disease, prediabetes or type 2 diabetes.
The National Drug Formulary’s local product information provides further details about the indication and prescribing information.
Meeting a BMI criterion does not automatically mean that treatment will be prescribed. Assessment also considers medical history, existing medicines, previous treatment, nutritional needs and relevant risks.
Mounjaro Price in Singapore
The indicative Mounjaro medication-only cost is approximately S$600–1,500 per month, depending on the prescribed dose and quantity supplied.
This range covers the medication itself. It excludes consultation fees, investigations, follow-up fees, delivery and other service charges where these apply.
The final quotation should specify:
- The prescribed strength
- The quantity of medication supplied
- The treatment period covered
- Any separate care or service charges
- Whether GST is included
A quoted monthly medication cost should not be assumed to represent the total cost of treatment.
The appropriate medicine and dose are determined following medical assessment. They should not be selected solely according to price.
What Can Affect the Cost of Mounjaro?
Medication costs may vary with the prescribed dose, quantity supplied and duration of treatment.
Separately, the overall cost of care may include consultations, investigations and follow-up. These depend on the individual assessment and treatment plan.
When comparing quotations, check that they cover the same medication strength, quantity and treatment period. A medication-only quotation and a package including clinical services are not directly comparable.
Discuss the anticipated ongoing costs before proceeding with a treatment plan
Mounjaro vs Zepbound: What’s the Difference?
Mounjaro and Zepbound are different brands containing the same active ingredient, tirzepatide.
However, products containing the same ingredient can have different approved indications, presentations and regulatory status in different countries.
The FDA’s information on Zepbound describes its US approval for chronic weight management. That US approval does not establish registration or availability in Singapore.
Is Zepbound the same drug as Mounjaro?
Both contain tirzepatide, but the branded products and their local instructions should not be treated as automatically interchangeable.
Is Zepbound available in Singapore?
No. The Singapore National Drug Formulary’s tirzepatide listing currently lists only Mounjaro products.
Do not assume that an overseas brand is locally registered or available simply because it contains tirzepatide. Local status should be checked against current Singapore records.
Clinical Evidence for Tirzepatide
Clinical evidence includes the SURMOUNT programme in weight management and the SURPASS programme in type 2 diabetes.
Study findings should be interpreted according to the population, dose, duration and outcomes evaluated.
SURMOUNT-1
The SURMOUNT-1 clinical trial studied adults with obesity, or overweight with at least one weight-related complication, without diabetes.
At 72 weeks, mean body weight reductions were approximately:
- 15.0% with 5 mg
- 19.5% with 10 mg
- 20.9% with 15 mg
- 3.1% with placebo
Participants received lifestyle support. These figures are trial averages, not predicted results for an individual patient.
SURMOUNT-3
The SURMOUNT-3 trial evaluated tirzepatide in adults who had already lost at least 5% of their weight following an intensive lifestyle intervention.
Participants receiving tirzepatide experienced additional average weight reduction, while the placebo group experienced average weight regain.
The study’s selected population and preceding lifestyle programme matter when interpreting its results.
SURMOUNT-4
The SURMOUNT-4 trial examined continued treatment and treatment withdrawal after an initial period of tirzepatide use.
Participants who continued treatment maintained and extended their weight reduction, while those switched to placebo experienced substantial weight regain.
This supports discussing longer-term care rather than assuming that a short course will produce permanent results.
Longer-term evidence
A longer-term SURMOUNT-1 analysis followed participants with obesity and prediabetes for 176 weeks.
Weight reduction remained substantial in the tirzepatide groups, and progression to type 2 diabetes was lower than in the placebo group.
These findings relate to that study population. They do not replace an individual assessment or establish a separate treatment indication.
How Much Weight Can You Lose With Mounjaro?
Clinical trials have demonstrated substantial average weight reduction with tirzepatide in adults with overweight or obesity.
For example, in SURMOUNT-1, average weight reduction at 72 weeks ranged from approximately 15% to 21%, depending on the tirzepatide dose studied.
However, these are clinical trial averages, not guaranteed individual outcomes.
Your response to treatment may be influenced by factors including:
- Starting weight
- Prescribed dose
- Duration of treatment
- Diet and physical activity
- Other health conditions
- Other medications
- Individual response to treatment
A doctor can discuss what may be realistic and clinically appropriate for you.
Mounjaro Dosage and Administration
Mounjaro is administered by injection under the skin once weekly.
The published adult dosing schedule starts at 2.5 mg weekly, increasing to 5 mg after four weeks. Further increases, where needed, occur in 2.5 mg steps after at least four weeks on the current dose.
Follow the prescribing doctor’s directions and the local dosing and administration instructions.
Do not change the dose, frequency or injection technique without appropriate advice.
For additional explanation, see our guide to Mounjaro KwikPen injection sites and technique. Follow the instructions supplied with your prescribed device and ask your healthcare professional if you are unsure.
Mounjaro Side Effects
Like other prescription medicines, Mounjaro can cause side effects.
Common side effects
Gastrointestinal effects are among the most commonly reported adverse effects with tirzepatide. These may include:
- Nausea
- Diarrhoea
- Vomiting
- Constipation
- Abdominal discomfort
- Reduced appetite
These effects may be more noticeable during dose escalation and can vary between individuals.
Serious side effects and precautions
Severe persistent abdominal pain, significant vomiting or symptoms of a serious allergic reaction require medical attention.
Difficulty breathing, facial or throat swelling, or collapse require emergency care.
The Singapore product information describes relevant warnings, including pancreatitis, dehydration and low blood glucose when used with insulin or certain diabetes medicines.
Who Should Not Take Mounjaro?
Mounjaro may not be appropriate for everyone.
Before prescribing tirzepatide, your doctor should be informed about:
- Previous or current pancreatic problems
- Significant gastrointestinal conditions
- Gallbladder problems
- Previous serious allergic reactions to tirzepatide or its ingredients
- Pregnancy or plans to become pregnant
- Breastfeeding
- Other medicines you are taking
- Any relevant personal or family medical history
Tirzepatide should not be used without medical supervision.
If you are unsure whether Mounjaro is suitable for you, discuss your medical history with a doctor before starting treatment.
Contraception, Pregnancy and Breastfeeding
Tirzepatide can affect the reliability of oral hormonal contraception.
Local product information advises switching to a non-oral method or adding a barrier method for four weeks after starting and for four weeks after each dose increase.
Tirzepatide is not recommended during pregnancy. The product information advises discontinuation at least one month before a planned pregnancy.
Discuss breastfeeding and pregnancy plans with the prescribing doctor before treatment.
Mounjaro and Other Weight Management Approaches
Mounjaro is one of several prescription medicines that may be considered for weight management.
Other medicines may contain different active ingredients, such as semaglutide or liraglutide.
The most appropriate treatment depends on factors including:
- Medical history
- BMI and weight-related health conditions
- Existing medications
- Treatment goals
- Previous treatment response
- Potential side effects and contraindications
A doctor can help determine which treatment, if any, is appropriate.
How to Get Mounjaro in Singapore
Mounjaro is a prescription medicine and should be obtained through an appropriate healthcare provider.
At Sire and Dame, the treatment process includes:
- Complete an online medical assessment
- Attend a doctor consultation
- Discuss your medical history and treatment goals
- Receive a prescription if the doctor considers treatment appropriate
- Follow the prescribed treatment and administration instructions
- Attend follow-up consultations where clinically appropriate
A prescription is issued only when the doctor determines that treatment is medically appropriate.
Before your appointment, read our guide to preparing for a weight management consultation, including the medical history and current medicines to discuss with your doctor.
For information about the organisations publishing this guide, read about Sire and Cloud Clinic and Dame’s healthcare platform.
Why Medical Supervision Matters
Prescription injections should not be obtained from unauthorised sellers or unverifiable sources.
The HSA advisory on prescription medicines obtained through unauthorised channels explains the risks associated with inappropriate, counterfeit or uncertain-quality products.
Medical supervision allows the clinician to assess suitability, review other medicines, monitor tolerability and adjust the care plan when necessary.
Lifestyle and Weight Management
Medication is only one component of medical weight management.
For appropriate patients, treatment with Mounjaro is used alongside a reduced-calorie diet and increased physical activity.
Lifestyle measures may include:
- A balanced eating pattern appropriate to your nutritional needs
- Regular physical activity
- Adequate sleep
- Appropriate hydration
- Sustainable eating and activity habits
Your doctor can advise on lifestyle measures that are appropriate for your circumstances.
Expert Perspective – Dr Bosty Chan in The Straits Times
Dr Bosty Chan is the Medical Director of Sire and Dame and has discussed the changing role of prescription weight management medicines and telemedicine in Singapore.
His commentary has addressed the importance of combining access to modern medical treatments with appropriate medical assessment and supervision.
Frequently Asked Questions About Mounjaro in Singapore
Final Takeaway
Mounjaro is a prescription medicine containing tirzepatide, a dual GIP and GLP-1 receptor agonist.
In Singapore, Mounjaro is registered for type 2 diabetes and weight management in eligible adults. Clinical studies have demonstrated substantial effects on body weight and glycaemic control, but individual results and treatment suitability vary.
If you are considering Mounjaro, the appropriate next step is to discuss your medical history, current medications and treatment goals with a doctor.
Disclaimer: This page is for general educational information and does not replace medical advice. Mounjaro is a prescription medicine. Treatment is subject to medical assessment and a doctor’s prescription.
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